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For example, AAS may prematurely stop the lengthening of bones (premature epiphyseal fusion through increased levels of estrogen metabolites), resulting in stunted growth.
Other effects include, but are not limited to, accelerated bone maturation, increased frequency and duration of erections, and premature sexual development.
These derivatives are hydrolyzed to release free testosterone at the site of injection; absorption rate (and thus injection schedule) varies among different esters, but medical injections are normally done anywhere between semi-weekly to once every 12 weeks.
A more frequent schedule may be desirable in order to maintain a more constant level of hormone in the system.
Another male-specific side-effect that can occur is testicular atrophy, caused by the suppression of natural testosterone levels, which inhibits production of sperm (most of the mass of the testes is developing sperm).Injection is the most common method used by individuals administering AAS for non-medical purposes.